neonatal marfan syndrome life expectancy
Symptoms may include areas of thickened skin stiffness feeling tired and poor blood flow to the fingers or toes with cold exposure. The most serious complications involve the heart and aorta with an increased risk of mitral valve prolapse and aortic aneurysm.
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Marfan syndrome MFS is a rare multi-systemic genetic disorder that affects the connective tissue.
. Those with the condition tend to be tall and thin with long arms legs fingers and toes. Scleroderma is a group of autoimmune diseases that may result in changes to the skin blood vessels muscles and internal organs. They also typically have overly-flexible joints and scoliosis.
The disease can be either localized to the skin or involve other organs as well.
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